Thursday, May 12, 2016

Study




More than 40 million adults in the United States have or are at peril of developing osteoporosis, a disease characterized by low bone mass and structural weakening of bone tissue that increases bone fragility and remarkably increases the risk of bone fracture .Osteoporosis is most often associated with inadequate calcium intakes, but insufficient vitamin D contributes to osteoporosis by dropping calcium absorption .Although rickets and osteopathic are extreme examples of the effects of vitamin D deficiency, osteoporosis is an example of a long-term effect of calcium and vitamin D insufficiency. Adequate storage levels of vitamin D maintain bone strength and might help prevent osteoporosis in older adults, non-ambulatory individuals who have difficulty exercising, postmenopausal women, and folks on chronic steroid therapy .Normal bone are constantly being remodeled. During menopause, the balance between these process changes, resulting in more bone being resorted than rebuilt. Hormone therapy with estrogen and progesterone might be able to delay the onset of osteoporosis. Several medical groups and professional societies support the use of HRT as an option for women who are at increased risk of osteoporosis or fractures .Such women should converse this material with their health care providers. Most supplementation trials of the property of vitamin D on bone health also take in calcium, so it is difficult to isolate the effects of each nutrient. Among postmenopausal women and older men, supplements of both vitamin D and calcium result in small increases in bone sandstone attention throughout the skeleton. They also help to lessen fractures in institutionalized older populations, although the revenue is inconsistent in community-dwelling individuals .Vitamin D supplementation alone appears to have no effect on risk lessening for fractures nor does it appear to reduce falls amongst the aged .one widely-cited meta-analysis suggesting a defensive benefit of supplemental vitamin D against falls .has been severely critiqued .However, a large study of women aged 69 years followed for an average of 4.5 years found both subordinate and higher25(OH)D levels at baseline to be associated with a greater risk of frailty .Women should consult their healthcare providers about their needs for vitamin D (and calcium) as part of an overall table to prevent or treat osteoporosis.

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